修改的查尔森并发症指数作为肝移植后老年患者的生存预测工具
Jiho Choi1, Eun-Woo Choi1, YoungRok Choi1
1Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Annals of surgical treatment and research
|June 20, 2023
概括
修改后的查尔森并发症指数 (mCCI) 可以预测老年人肝移植 (LT) 存活率. 在这组患者中,5因素修改的脆弱指数 (mFI-5) 并不是一个显著的预测指标.
科学领域:
- 老年医学 老年医学
- 移植手术 移植手术
- 肝病学 肝病学是一种肝病学.
背景情况:
- 肝移植 (LT) 越来越多地在老年患者中进行.
- 目前的预后工具并没有专门预测老年LT接受者的结果.
- 预测老年人移植后的生存率对于优化护理至关重要.
研究的目的:
- 评估修改的查尔森并发症指数 (mCCI) 和5因素修改的脆弱指数 (mFI-5) 对65岁以上患者的LT后生存的预测值.
- 确定可靠的工具来评估老年肝移植接受者的预后.
主要方法:
- 对155名65岁以上的患者进行了回顾性分析,这些患者接受了LT.
- 根据mCCI和mFI-5得分,患者被分为低和高分层.
- 使用考克斯回归分析来确定变量对生存的独立影响.
主要成果:
- 较高的mCCI得分与较低的1个月,3个月,1年,3年和5年的生存率显著相关.
- 末期肝病 (MELD) 的mCCI,性别和模型得分是生存的重要预测因素.
- mFI-5没有显示对LT后生存的显著影响.
结论:
- 在老年患者中,mCCI是预测LT后存活率的宝贵工具.
- 此外,MELD得分仍然是这一群体的重要预测指标.
- 进一步的研究可能会完善老年LT候选人的脆弱性评估.
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