缺血性中风后的功能恢复:不同睡眠健康参数的影响
Claire Denis1, Isabelle Jaussent2, Lily Guiraud1
1Sleep-Wake Disorders Unit, Department of Neurology, Gui-de-Chauliac Hospital, CHU, Montpellier, France.
Journal of sleep research
|June 20, 2023
概括
缺血性中风后,睡眠呼吸暂停等睡眠障碍是常见的. 这些,以及失眠和不安腿综合征,与较差的功能结果有关,但CPAP治疗没有显著的益处.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 康复 康复 康复 康复
背景情况:
- 缺血性中风后经常出现睡眠障碍,影响恢复.
- 常见的问题包括睡眠呼吸暂停,失眠和不安腿综合征.
- 持续正气道压力 (CPAP) 是严重阻塞性睡眠呼吸暂停的潜在治疗方法.
研究的目的:
- 为了研究睡眠障碍对功能结果的影响,中风后3个月.
- 评估CPAP在患有严重阻塞性睡眠呼吸暂停的患者中的疗效.
主要方法:
- 90名缺血性中风患者接受了睡眠查和多睡眠学.
- 患有严重阻塞性睡眠呼吸暂停 (AHI ≥30) 的患者随机分配到CPAP或假药治疗中.
- 功能独立性 (巴特尔指数),残疾 (修改的兰金分数) 和NIH中风量表在3个月后被评估.
主要成果:
- 51%的患者患有阻塞性睡眠呼吸暂停,21.3%患有严重的呼吸暂停.
- 在OSA严重程度组之间或在CPAP和假组之间没有观察到功能结果的显著差异.
- 较差的结果与失眠,不安腿综合征,抑郁症和睡眠时间/REM睡眠减少有关,而不是AHI严重程度.
结论:
- 睡眠障碍在中风后很普遍,但在这个队列中没有显著影响3个月的功能结果.
- 在这项研究中,CPAP治疗对严重阻塞性睡眠呼吸暂停没有显著的益处.
- 失眠,RLS,抑郁症和睡眠质量下降与更糟糕的结果有关,需要进一步调查.
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