与湿疹相关的因素 临床试验 成年人的意识,兴趣和参与
Erin E Grinich1, Isabelle J Thibau2, Emile Latour3
1Department of Dermatology, Oregon Health & Science University, Chicago, IL, US.
Acta dermato-venereologica
|June 20, 2023
概括
低参与湿疹临床试验是一个挑战. 诸如对当前治疗方法的更高满意度,更好的临床试验素养,以及对寻找信息的信心等因素,提高了湿疹患者的意识和兴趣.
科学领域:
- 皮肤病学 皮肤病学
- 临床研究 临床研究
- 患者参与 患者参与
背景情况:
- 湿疹治疗需要创新,但临床试验参与率很低.
- 了解患者的障碍对于增加在湿疹研究中的招生至关重要.
研究的目的:
- 确定影响湿疹患者意识,兴趣和参与临床试验的因素.
- 探索在皮肤病学研究中招生和参与的障碍.
主要方法:
- 2020年5月1日至6月6日,美国针对患有湿疹的成年人进行了一项在线调查.
- 800名参与者 (平均年龄49.4,女性78.1%,白人75.4%) 完成了调查.
- 数据分析的重点是患者特征,试验素养和参与之间的关联.
主要成果:
- 只有9.7%的湿疹患者报告了之前的临床试验经验.
- 对于当前的湿疹治疗,临床试验素养和信息寻找信心的更高满意度与提高意识,兴趣和参与度相关.
- 年龄较小和亚托皮性皮炎诊断与更高的认识有关;女性性别对兴趣和参与构成障碍.
结论:
- 提高临床试验素养和患者对获取信息的信心可以提高湿疹试验参与度.
- 解决性别特异性障碍是必要的,以加强女性参与皮肤病学临床试验.
- 需要有针对性的策略来克服在湿疹研究中的低入学率.
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