在临床试验后评估第二次疼痛治疗的益处
Tracy M Anastas1, Aaron P Turner1, Erica J Ho1
1Rehabilitation Care Service, VA Puget Sound Health Care System.
Rehabilitation psychology
|June 20, 2023
概括
在疼痛治疗试验后添加一个开放标签阶段显示了价值. 许多参与者注册并发现了好处,为患者的经验和慢性疼痛管理的治疗偏好提供了见解.
科学领域:
- 疼痛管理研究 疼痛管理研究
- 临床试验设计 临床试验设计
- 患者报告的结果
背景情况:
- 慢性疼痛影响了许多退伍军人,需要有效的治疗策略.
- 随机对照试验 (RCT) 对于评估疼痛干预措施至关重要.
- 在治疗疼痛的RCT之后,开放标签阶段的实用性尚未得到充分证实.
研究的目的:
- 评估在疼痛治疗临床试验后纳入开放标签阶段的价值.
- 检查参与者特征和公开标签阶段的感知好处.
- 了解患者在疼痛管理方面的偏好和经验.
主要方法:
- 对患有慢性疼痛的退伍军人进行二次数据分析.
- 参与者完成了一项随机对照试验 (RCT),比较了催眠,正念冥想和疼痛教育.
- 随着RCT的开放标签阶段,评估疼痛强度,干扰,抑郁和满意度.
主要成果:
- 40%的符合条件的退伍军人参加了开放标签阶段.
- 报名者更有可能年龄较大,参加更多的RCT会议,并对初始治疗感到满意.
- 开放标签阶段显示抑郁症和最严重的疼痛减少;大多数退伍军人感觉到改善并感到满意.
结论:
- 疼痛治疗试验后的开放标签阶段似乎是有价值的.
- 很大一部分参与者注册并报告了好处.
- 开放标签数据可以揭示患者的经验,护理障碍/促进者以及治疗偏好.
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