坚持延长静脉血栓栓塞的预防和复杂的胃肠道瘤手术后的结果
Michail N Mavros1, Lauren A Johnson2, Mario Schootman3
1Department of Surgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA. mmavros@uams.edu.
Annals of surgical oncology
|June 20, 2023
概括
大多数接受重大胃肠道手术的癌症患者没有接受延长静脉血栓塞栓症 (VTE) 预防. 这并没有增加他们患静脉瘤或出院后出血的风险.
科学领域:
- 在瘤学瘤学.
- 手术 手术 手术
- 药理学 药理学是指药理学的学科.
背景情况:
- 临床指南建议扩展静脉血栓塞栓症 (VTE) 预防癌症患者进行重大胃肠道 (GI) 手术后.
- 遵守这些VTE预防指南的程度很低,临床结果仍未确定.
研究的目的:
- 评估延长VTE预防与接受重大胃肠道手术的癌症患者的临床结果之间的关联.
- 评估VTE和出血率与准则的遵守有关.
主要方法:
- 来自IQVIA LifeLink PharMetrics Plus数据库 (2009-2022) 10%的样本进行了回顾性分析.
- 包括癌症患者接受主要的胰腺,肝脏,胃或食道手术.
- 主要结局是出院后90天的VTE和出血事件.
主要成果:
- 分析了2296个符合条件的操作;10.4%接受了扩展的VTE预防.
- 出院后的VTE发生在5.2%的患者中,出血发生在5.2%的患者中.
- 延长VTE预防没有显著的关联与下院后减少VTE (OR 1.54) 或出血 (OR 0.72).
结论:
- 大多数接受了复杂的肠道外科手术的癌症患者没有按照指导方针接受延长的静脉瘤预防.
- 不接受延长预防的患者与接受延长预防的患者相比,并没有与更高的静脉瘤发作率有关.
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