生物标志物及其与肥胖女性心血管风险参数的关系
Bruna Emanuele Pereira Cardoso1, Tamires da Cunha Soares2, Thaline Milany da Silva Dias2
1Department of Nutrition, Federal University of Piaui, Teresina, Brazil. brunaemanuelec@hotmail.com.
Biological trace element research
|June 20, 2023
概括
肥胖女性的摄入量较低,尿液含量较高,心血管风险因素增加. 可能在肥胖中起到对心血管疾病的保护作用.
科学领域:
- 营养生物化学 营养生物化学
- 心血管健康 心血管健康
- 人体生理学 人体生理学
背景情况:
- 肥胖是一个全球性健康问题,与心血管疾病 (CVD) 风险增加有关.
- 是一种具有抗氧化特性的微量元素,可能会影响新陈代谢和心血管健康.
- 的营养状况及其与肥胖和心血管疾病风险因素的关系需要进一步调查.
研究的目的:
- 为了研究状态 (饮食摄入量,血,红细胞和尿液度) 与肥胖女性心血管风险参数之间的关联,与肥胖女性相比.
- 探索水平与心血管风险的各种人体测量和生化标志物之间的相关性.
主要方法:
- 一项涉及210名女性 (84名肥胖,126名肥胖) 的横截面研究.
- 测量包括人体测量 (体重,身高,卫生间,部/部周长),脂质概况,血压,以及血,红细胞和尿液中的水平.
- 计算的腰比,圆度指数和卡斯特利指数.
主要成果:
- 肥胖妇女的平均饮食摄入量和血/红细胞度显著较低,但尿度较高,而非肥胖妇女.
- 肥胖女性表现出心血管风险参数升高,包括腰围,子周长,腰比,圆度指数,三糖醇 (TGC) 和VLDL-c.
- 在血和总胆固醇,非高密度胆固醇,LDL-c和SBP之间观察到负相关性. 饮食中的与几个心血管疾病风险标志物有负相关性,与HDL-c和DBP有正相关性.
结论:
- 肥胖妇女的营养状况发生变化,心血管风险增加.
- 研究结果表明,在减轻肥胖的背景下减轻心血管疾病风险方面具有潜在的保护作用.
- 需要进一步的研究,包括干预研究,以证实在肥胖人群中预防心血管疾病中的作用.
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