负控制:概念和警告
Bas Bl Penning de Vries1, Rolf Hh Groenwold2,3
1Julius Center for Health Sciences and Primary Care, Utrecht University Medical Center, Utrecht, The Netherlands.
Statistical methods in medical research
|June 20, 2023
概括
负控制是检测因果推理中未测量的混偏差的工具. 然而,它们可能缺乏敏感性和特异性,因此需要仔细对疫情学实践进行逐案评估.
科学领域:
- 流行病学 流行病学
- 因果推理因果推理
- 生物统计学 生物统计学
背景情况:
- 在确定因果关系方面,未测量的混是一个重大挑战.
- 负控制已经成为解决未测量的混问题的潜在工具.
- 在流行病学实践中,负控制的使用正在迅速扩大.
结论:
- 虽然负控制有希望,但它们的常规使用需要仔细考虑限制和假设.
- 未来的研究可能会提高负控的适用性和可靠性.
- 对于每项流行病学研究,应单独评估目前的适用性.
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