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在患有多发性硬化症的年轻患者中,MRI标志着退行性磁盘疾病

Nima Omid-Fard¹, Rebecca E Thornhill¹, Carlos Torres¹

¹Department of Radiology, University of Ottawa, ON, Canada.

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

|June 20, 2023

概括

年轻的多发性硬化症 (MS) 患者的宫性退行性磁盘疾病 (DDD) 发病率很高. 这些患者的带病变发现独立于DDD发生.

科学领域:

神经学神经学
放射学放射学是一门学科.
脊髓医学脊髓医学

背景情况:

新出现的证据表明,退行性磁盘疾病 (DDD) 和多发性硬化症 (MS) 之间存在联系.
在年轻的多发性硬化症患者 (年龄在35岁以下) 中,宫DDD仍未得到充分研究.

研究的目的:

在被诊断为MS的年轻患者中调查宫DDD的患病率和严重程度.
在这个人口群体中评估宫DDD和脊髓信号异常之间的关系.

主要方法:

在2005年至2014年期间,对80名多发性硬化症患者 (年龄<35岁) 的MRI扫描进行了回顾性审查.
三名独立评级人员使用新型分级尺度对DDD和电缆信号异常的评估.
统计分析包括使用肯德尔的W和弗莱斯的卡帕.

主要成果:

在DDD分级尺度上实现了高的分级间可靠性.
超过91%的年轻多发性硬化患者表现出某种程度的宫DDD,主要是轻度至中度.
脊髓信号异常在56-63%的患者中存在,并且在10-15%的患者中独立于DDD水平发生.

结论:

患有多发性硬化症的年轻患者经常出现椎退行性磁盘疾病.
这种关联的病因,可能涉及生物力学因素,需要进一步调查.
在MS中脊髓病变似乎独立于椎椎间盘退行性疾病而发展.

关键词:

退行性磁盘疾病是一种退行性磁盘疾病.脱髓化疾病是一种脱髓化疾病.多发性硬化症多发性硬化症脊髓斑块是因为脊髓斑块.脊柱MRI是指脊柱的MRI.脊椎病是指脊椎病的一种疾病.

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Magnetic Resonance Imaging

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