口内冷却对味觉和嗅觉感知的影响
Vian Hussaini1, Samaa Wasmi2, Java Walladbegi2
1Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.
Acta odontologica Scandinavica
|June 20, 2023
概括
用冰片进行口腔内冷却会暂时降低健康个体的味觉和嗅觉感知. 虽然效果往往会恢复到基线,但一些味道变化可能会在冷却后持续存在.
科学领域:
- 在瘤学瘤学.
- 感官科学 感官科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 使用冰片的冷疗法是预防化疗引起的口腔粘膜炎的常见方法.
- 人们担心口内冷却对味觉和嗅觉的潜在负面影响.
研究的目的:
- 研究口内冷却对味觉和嗅觉的长期影响.
- 为了确定冷治疗预防口腔粘膜炎是否会导致永久的感官缺陷.
主要方法:
- 20名健康受试者参与了这项研究.
- 试验对象使用冰片进行口内冷却60分钟.
- 在基线,冷却期间 (15-60分钟) 和冷却后 (T75) 评估了味道和气味感知,使用数值评分表与各种溶液和香味.
主要成果:
- 在整个冷却期间 (p < .05) 观察到化,糖和的味觉感知有统计学意义的减少.
- 酸味道和气味感知在冷却30分钟后受到显著影响.
- 虽然在冷却后15分钟 (T75) 发现了一些恢复,但所有测试溶液的味觉感知仍然与基线显著不同 (p < .01).
结论:
- 用冰片进行口腔内冷却会导致健康个体的味觉和嗅觉暂时下降.
- 在冷却停止后,感官知觉有倾向回到基线水平.
- 即使在冷却期结束后,味觉的持续变化也可能发生.
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