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Updated: Jul 26, 2025

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
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新型共价结合剂的基于结构的计算设计,用于治疗状细胞疾病

Abdeen Tunde Ogunlana1, Ibrahim Damilare Boyenle2, Taiwo Ooreoluwa Ojo3

  • 1Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.

Journal of molecular graphics & modelling
|June 20, 2023
PubMed
概括

研究人员探索了新的共价结合剂来治疗状细胞疾病 (SCD),灵感来自药物Voxelotor. 计算方法确定了三个有前途的候选药物,有可能改善对HbS聚合物的治疗反应.

关键词:
基于共价对接的选.模拟MD的模拟方法在MM/PBSA中,可以选择MM/PBSA.状细胞疾病 (SCD) 是一种状细胞疾病.这是一个Voxelotor.

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