在一群埃及人中绘制肠道寄生虫模式的地图
Eman S El-Wakil1, Rabab S Zalat2, Ayman A El-Badry3
1Department of Parasitology, Theodor Bilharz Research Institute, Kornaish El-Nile St., Giza, 12411, Egypt. e.el-wakil@tbri.gov.eg.
Scientific reports
|June 20, 2023
概括
肠道寄生虫感染在埃及很常见,影响59.6%的患者. 农村居住显著增加了多种感染的风险,突出了改善卫生和获得水的必要性.
科学领域:
- 医学寄生虫学 医学寄生虫学
- 分子流行病学分子流行病学
- 公共卫生 公共卫生
背景情况:
- 肠道寄生虫感染在发展中国家仍然是一个重大的公共卫生问题,受到地理和社会经济因素的影响.
- 了解这些感染的分布和风险因素对于有针对性的干预至关重要.
研究的目的:
- 在埃及人口中绘制肠道寄生虫感染的分布图.
- 识别和评估与这些感染相关的风险因素,包括特定的寄生虫物种和组合.
主要方法:
- 一项涉及386名患者的横截面研究,收集便样本进行显微镜检查和DNA提取.
- 包括PCR,限制酶分析和测序在内的分子技术被用于识别和分类各种原生动物:Entamoeba histolytica复合物,Cryptosporidium,Giardia intestinalis和Blastocystis物种.
- 植物遗传学分析被用来识别胚胎囊亚型.
主要成果:
- 总体感染率为59.6%,其中87.4%的受感染者患有单次感染,12.6%患有多次感染.
- 囊胚菌,Entamoeba histolytica复合体和Giardia intestinalis是最常见的原生动物.
- 分子鉴定揭示了布拉斯托体ST3,Entamoeba dispar,Giardia intestinalis组合B和Cryptosporidium hominis作为最常见的物种.
- 感染患病率与年龄,性别,居住地和水源有明显的关联.
- 农村居民成为多种寄生虫症的重要危险因素 (OR 4.49).
结论:
- 埃及人群,特别是农村地区的人群,表现出肠道寄生虫感染的高患病率,包括多种寄生虫.
- 以健康教育,个人卫生和安全用水供应为重点的有针对性的控制策略对于减轻这些感染对脆弱社区的影响至关重要.
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