基本金属元素混合物与中国社区老年人的睡眠质量之间的关联
Hongli Wang1,2, Yan Zhang1,2, Huaibiao Li3
1School of Public Health, Department of Epidemiology and Health Statistics, Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui, China.
Biological trace element research
|June 20, 2023
概括
这项研究发现,尿液中较高水平的必需金属元素 (EME),特别是,和,与老年人更好的睡眠质量有关. 这些金属的联合作用也显示出与睡眠的保护性关联.
科学领域:
- 环境健康 环境健康
- 老年学是一门学科.
- 营养科学 营养科学
背景情况:
- 之前的研究已经探讨了个别的基本金属元素 (EME) 以及它们对老年人睡眠质量的影响.
- 在这个人群中,EME混合物对睡眠质量的综合影响仍未得到充分研究.
- 了解这些关系对于针对与年龄有关的睡眠障碍的公共卫生倡议至关重要.
研究的目的:
- 研究单个EME和尿液中的EME混合物与中国老年人睡眠质量的关联.
- 确定有助于或防止该人口睡眠质量差的特定EME.
主要方法:
- 一项涉及3957名来自中国社区的老年人 (60岁以上) 的横截面研究.
- 测量了7种EME (,,,,,,,,) 的尿度,使用诱导合血质谱法.
- 使用匹兹堡睡眠质量指数 (PSQI) 评估睡眠质量.
- 用物流回归和贝叶斯核机器回归 (BKMR) 模型来分析这些关联.
主要成果:
- 单元物流回归显示了 (Mo), (Sr) 和 (Mg) 与睡眠质量差之间的负面关联.
- 贝叶斯核机器回归 (BKMR) 证实了这些发现,表明EME混合物与睡眠质量差的几率之间存在反向关系.
- (Mo) 呈现了最高的条件后部包含概率,这表明它是EME混合物中最重要的贡献者.
结论:
- 该研究得出的结论是,较高的必需金属元素混合物的尿液水平与老年人睡眠质量差的几率降低有关.
- ,和单独或混合显示出对睡眠不良的保护作用.
- 建议进行进一步的队列研究,以阐明多个EME与老龄人口的睡眠质量之间的复杂关系.
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