系统氧气消耗与年龄和全身麻醉下体温的关联:回顾性队列研究
Satoshi Kimura1, Kazuyoshi Shimizu2, Hiroshi Morimatsu2
1Department of Anesthesiology and Resuscitology, Okayama University Hospital, 2-5-1, Shikata-Cho, Kita-Ku, Okayama, 700-8558, Japan. kimsato1034@hotmail.co.jp.
BMC anesthesiology
|June 20, 2023
概括
在18岁以下的个体中,氧气消耗 (VO2) 随着年龄的增长而下降. 在高温症期间,VO2随体温增加而增加,但在低温症期间保持稳定,新生儿和婴儿表现出显著的反应.
科学领域:
- 生理学 生理学 生理学
- 麻醉学 麻醉学
- 代谢研究 代谢研究
背景情况:
- 系统氧气消耗 (VO2) 与体温 (BT) 有关,但在广泛的BT范围内对人类的研究有限.
- 研究VO2和BT之间的关系对于理解代谢调节至关重要.
研究的目的:
- 为了确定氧气消耗 (VO2) 和年龄之间的关联.
- 为了确定氧气消耗 (VO2) 和体温 (BT) 之间的关联.
主要方法:
- 对7567名在全身麻醉下进行手术的患者进行了回顾性分析.
- 使用Drager Perseus A500麻醉工作站测量VO2.
- 使用随机效应的分线和多变量回归分析用于检查关联.
主要成果:
- 在18岁以下的患者中,VO2每年减少2.1毫升/千克/分钟;在老年患者中没有显著变化.
- 在BT<36.0°C与36.0-36.5°C相比,VO2没有显著差异.
- 在BT升高超过36.5°C时观察到VO2的显著增加,特别是在超热状态 (BT≥37.5°C) 中.
结论:
- 氧气消耗 (VO2) 在高温症中随体温 (BT) 升高,但在低温症中保持不变.
- 新生儿和婴儿表现出大量的系统器官对VO2对BT波动的反应,这是由于它们固有的高VO2水平.
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