尿转移装置可能会影响尿颗粒结果:一个分析前研究
Nathan Debunne1, Joris Delanghe2, Leen Raman1
1Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium.
Clinical chemistry and laboratory medicine
|June 21, 2023
概括
输尿管可以改变粒子计数,影响诊断的准确性. 实验室应该意识到尿液采集方法的这些差异,以获得可靠的结果.
科学领域:
- 临床诊断 临床诊断 临床诊断
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医学实验室科学 医学实验室科学
背景情况:
- 标准化的预分析程序对于可靠的尿液诊断至关重要.
- 调查采集方法对尿液分析的影响至关重要.
研究的目的:
- 评估不同尿液收集方法和输送管对尿液试管和颗粒分析的影响.
- 为了确定尿液转移是否会影响化学和颗粒分析结果.
主要方法:
- 使用各种收集容器和转移管 (BD,格莱纳,萨斯特德真空,萨斯特德吸收) 检测了146个尿样.
- 通过光流细胞计 (Sysmex UF-5000) 进行化学试验带分析 (Sysmex UC-3500) 和粒子分析.
- 原始样本作为参考,直接测量在分析仪上.
主要成果:
- 在转移方法之间没有观察到测试带结果的显著差异.
- 尿液转移到二次管道显著影响了颗粒数量.
- 在BD和格林纳管中,脏管状上皮细胞和素体的减少被观察到.
- 用BD,格莱纳和萨斯特特真空管减少了病态造数量.
结论:
- 输尿管可以影响脆弱尿粒的计数.
- 临床实验室必须识别尿液采集方法对颗粒数量引入的变化.
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