肺微生物群:它与呼吸系统疾病的关系以及针对肺的益生菌细菌输送的方法
Nilufer Yuksel1, Busra Gelmez2,3, Ayca Yildiz-Pekoz4
1Department of Pharmaceutical Technology, Faculty of Pharmacy, Ankara University, 06560 Ankara, Turkey.
Molecular pharmaceutics
|June 21, 2023
概括
益生菌可以帮助平衡呼吸道微生物,为预防和治疗慢性肺部疾病提供潜力. 需要对肺向益生菌输送进行进一步研究.
科学领域:
- 微生物学 微生物学
- 肺部病理学 肺部病理学
- 免疫学 免疫学 免疫学
背景情况:
- 人类微生物群,包括肠道和肺部微生物,显著影响健康和疾病.
- 肠-肺轴描述了肠和肺之间的双向通信.
- 新兴研究强调了肺微生物群在呼吸系统健康中的重要性.
研究的目的:
- 审查益生菌在调节呼吸道微生物群中的作用.
- 检查肺部微生物群与各种呼吸道疾病之间的关系.
- 探索益生菌在肺部健康中的应用的未来前景.
主要方法:
- 1977年至2022年间发表的研究文献综述.
- 对人类微生物群,肠肺轴和呼吸道微生物群的研究分析.
- 检查肺微生物群与COPD,喘,肺炎和COVID-19等疾病之间的联系.
主要成果:
- 益生菌在维持呼吸道微生物平衡方面发挥着关键作用.
- 目前,关于益生菌在慢性肺部疾病中的预防或治疗用途的研究有限.
- 该审查涵盖了益生菌作用机制和制药配方方法.
结论:
- 益生菌通过影响肺部微生物群来管理呼吸系统疾病有希望.
- 对肺向益生菌的进一步研究是有必要的,以获得预防和治疗的好处.
- 肠肺轴为了解益生菌对呼吸系统健康的影响提供了一个框架.
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