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校正:基于脂质纳米粒子的配方,用于高性能牙科应用.

Isha Mutreja1, Dhiraj Kumar2, Ajeet Kaushik3

  • 1Minnesota Dental Research Center for Biomaterials and Biomechanics, Department of Restorative Sciences, University of Minnesota, Moos Health Science Tower, 515 Delaware Street S.E., Minneapolis, MN 55455, USA. imutreja@umn.edu.

Journal of materials chemistry. B
|June 21, 2023
PubMed
概括

这项修正澄清了先前关于用于先进牙科应用的脂质纳米粒子配方研究的细节. 它确保了对牙科生物材料感兴趣的读者的准确性.

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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