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塞罗瓦尔Typhi使用两种类型3分泌系统在人类巨细胞中复制并殖民化小鼠

Meagan Hamblin1, Ruth Schade1, Ramya Narasimhan1

  • 1Department of Microbiology and Immunology, Stanford University School of Medicine , Stanford, California, USA.

mBio
|June 21, 2023
PubMed
概括

沙门氏菌使用两种3型分泌系统 (T3SS-1和T3SS-2) 在人体巨细胞内复制. 这两种T3SS都对细菌毒性和在伤寒感染期间的殖民性至关重要.

关键词:
在T3SS-1中使用.在T3SS-2中使用.病变的发生和发病.伤寒发烧 伤寒发烧是什么?典型的伤寒病毒是什么?

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Gram-negative bacteria utilize sophisticated protein secretion systems to transport proteins across their double-membrane envelope into the extracellular environment or host cells. Based on their mechanism of action, these systems are classified into one-step and two-step pathways.One-Step Secretion Systems (Types I, III, IV, and VI)One-step secretion systems bypass the periplasm entirely, forming a continuous channel that spans both the inner and outer membranes:Type I Secretion System (T1SS):...
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