在土耳其的中亚纳托利亚地区的儿童类 Sarcoidosis
Melih Hangül1, Mehmet Köse1, Sevgi Pekcan2
1Division of Pediatric Pulmonology, Department of Pediatrics, Erciyes University, Kayseri, Turkey.
Pediatric pulmonology
|June 21, 2023
概括
晚期发病的儿童沙尔科发症在土耳其儿童中呈现独特,咳是最常见的初始症状. 系统性类固醇治疗对大多数患者有效,突出了新的区域发病率和呈现模式.
科学领域:
- 儿科肺病学 儿科肺病学
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- Sarcoidosis 是一种多系统性炎症性疾病,病因不明.
- 晚期发病的儿童肉类发病症是罕见的,其临床特征可以显著变化.
- 了解呈现和处理的区域差异对于有效管理至关重要.
研究的目的:
- 描述土耳其队列中晚期发病的儿童肉类发病症的临床,放射和实验室特征.
- 概述使用的诊断方法,器官参与和治疗策略.
- 将发现与现有的国际文献进行比较.
主要方法:
- 在2012年至2022年期间,对22名被诊断患有沙尔科毒症的儿科患者进行了回顾性多中心研究.
- 审查医疗记录,包括临床表现,实验室结果,成像和治疗结果.
- 数据分析以确定常见的症状,实验室异常和治疗反应.
主要成果:
- 诊断时的平均年龄为13.1岁;咳是最常见的症状 (40.9%).
- 较高的C-反应蛋白 (CRP),血管酶转化酶 (ACE),红细胞沉积率 (ESR) 和免疫球蛋白G (IgG) 是常见的.
- 90%的患者接受了全身类固醇治疗,阳性反应率为81.8%.
结论:
- 这项研究提供了关于土耳其儿童肉类瘤发病率和表现的新见解,咳是主要症状.
- 血缘婚姻的更高的流行率被注意到,这与之前的研究不同.
- 这些发现有助于欧洲关于儿科沙尔科病的有限数据,强调需要进一步研究.
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