左心室功能障碍在角性多变性心肌病:通过心血管磁共振特征跟踪评估
Yingxia Yang1,2, Minjie Lu3, Xuechun Guan1
1Department of Radiology, The First Affiliated Hospital of Guangxi Medical University.
Journal of thoracic imaging
|June 21, 2023
概括
在典型和亚临床患者中,缩性缩性心肌病 (AHCM) 损害了左心房 (LA) 储水池和导管功能. 心血管磁共振特征追踪 (CMR-FT) 有效量化这些功能缺陷.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
背景情况:
- 亚皮性多变性心肌病 (AHCM) 是一种独特的多变性心肌病形式.
- 左心房 (LA) 功能在心血管健康中起着至关重要的作用.
- 评估AHCM中的LA功能可以提供有关疾病机制和进展的见解.
研究的目的:
- 通过心血管磁共振特征追踪 (CMR-FT) 来评估角性多变心肌病 (AHCM) 患者的左心房 (LA) 功能.
- 为了比较典型的AHCM (TAHCM),亚临床AHCM (SAHCM) 和健康对照之间的LA功能.
主要方法:
- 对30名TAHCM患者,23名SAHCM患者和32名接受CMR的健康对照进行了回顾性分析.
- 使用体积学和CMR-FT衍生的应变和应变率 (SR) 参数量化LA储,导管和收缩功能的量化.
- 对2和4电影成像的分析.
主要成果:
- 与对照组相比,TAHCM和SAHCM患者均表现出LA储和导管功能受损.
- 动脉动脉储和导管应变与左心室质量指数和最大壁厚有显著的相关性.
- 虽然保持了活性排空分数和应变,但TAHCM患者显示了最低的活性SR.
结论:
- 左心房 (LA) 储和导管功能主要在亚临床和典型的缩性心肌病 (AHCM) 患者中受损.
- CMR-FT是评估AHCM中LA功能缺陷的一个有价值的工具.
- 这些发现凸显了AHCM对心房功能的影响.
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