在患有自发前头骨底部脑脊液泄漏的患者中,持续性鼻狭窄
Karim W Asi1, Brian H Cameron1, Elliot R Friedman2
1Department of Otorhinolaryngology-Head and Neck Surgery, McGovern Medical School The University of Texas Health Science Center at Houston Houston Texas USA.
Laryngoscope investigative otolaryngology
|June 21, 2023
概括
持续静脉鼻狭窄在自发脑脊液泄漏的患者中很常见,发生在80%的病例中. 这种患病率明显高于一般人群,这表明潜在的联系和诊断实用性.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 神经外科 神经外科
背景情况:
- 异常性内高血压 (IIH) 与自发性脑脊液 (sCSF) 泄漏和持续静脉鼻 (DVS) 狭窄有关.
- 关于DVS缩小和sCSF泄漏之间的关系的数据有限.
研究的目的:
- 为了确定患有中枢神经流泄漏的患者中DVS缩小的患病率.
- 为了将sCSF泄漏患者的DVS缩小患病率与一般人群进行比较.
主要方法:
- 从2008年至2019年,对25名患有中枢神经瘤泄漏的患者进行了回顾性审查.
- 两个神经放射学家对手术前成像进行独立审查,以发现DVS缩小.
- 使用精确二项式测试,与一般人群中DVS缩小的文献数据进行比较.
主要成果:
- 80%的患者 (20/25) 患有sCSF泄漏,显示DVS缩小.
- 大多数受影响的患者是女性 (84%),平均年龄为51.89岁.
- 与一般人群相比,SCSF泄漏患者的DVS缩小患病率显著高 (80%),比一般人群高 (40%,p < .001).
结论:
- 在患有中枢神经流泄漏的患者中,DVS缩小明显普遍,超过一般人群的比率.
- 大肠静脉狭窄可能是中枢神经液泄漏的未被诊断的原因.
- 在手术前对DVS进行MR静脉扫描评估可能有助于诊断SCSF泄漏.
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