艾滋病毒感染者同时使用香烟和大麻:随机对照戒烟试验的结果
Jenny E Ozga1, Jonathan Shuter2,3, Geetanjali Chander4
1Behavioral Health and Health Policy Practice, Westat, Rockville, MD, USA.
Drug and alcohol dependence reports
|June 21, 2023
概括
对于吸烟的艾滋病毒感染者 (PWH),在六个月内增加大麻使用频率与戒烟的几率降低有关. 这凸显了需要理解在戒断计划中同时出现的物质使用.
科学领域:
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
- 行为科学 行为科学
背景情况:
- 与一般人群相比,艾滋病毒感染者 (PWH) 的戒烟率较低.
- 了解影响PWH戒烟的因素对于开发有效干预措施至关重要.
研究的目的:
- 调查大麻使用频率的变化是否会阻碍PWH中吸烟者戒烟的动机.
- 检查PWH中大麻使用变化与吸烟禁欲之间的关联.
主要方法:
- 一个随机对照试验,涉及PWH吸烟者,他们有戒烟的动力 (2016-2020).
- 在基线,1,3,6个月 (N=374) 分析过去30天的大麻使用情况.
- 多变量逻辑回归用于评估6个月大麻使用频率和戒烟的变化.
主要成果:
- 在至少使用一次大麻的PWH中 (n=198),不使用的比例从基线18.2%增加到6个月后的34.3%.
- 与起始值相比,大麻使用频率的增加与使用率下降相比,在6个月后戒烟的几率显著降低 (aOR=0.22).
- 增加大麻使用也与减少戒断的几率有关,与在任何时间点不使用大麻相比 (aOR=0.25).
结论:
- 在6个月的时间里,增加大麻的使用与PWH中吸烟禁欲的几率较低有关.
- 需要进行进一步的研究,以探索影响同时使用大麻和戒烟的其他因素.
- 在PWH中戒烟的干预措施可能需要考虑大麻使用模式.
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