在光学散射的存在下,开启和关闭感应场处理
Katharina Breher1,2, Antonia Neumann2, Dominik Kurth2
1Carl Zeiss Vision International GmbH, Turnstr. 27, 73430 Aalen, Germany.
Biomedical optics express
|June 21, 2023
概括
视网膜的ON/OFF路径处理在近视和非近视之间有所不同. 对比度降低没有影响这些视觉处理差异,这挑战了其在近视控制中的使用.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 视觉科学 视觉科学
背景情况:
- 视网膜ON/OFF通路激活的平衡对于体外化至关重要.
- 近视控制策略正在探索减少对比度以调节视觉处理.
研究的目的:
- 为了研究近视者与非近视者的ON/OFF感应场处理.
- 为了确定对比度降低对ON/OFF路径灵敏度的影响.
主要方法:
- 一种心理物理方法测量了22名参与者的开启和关闭对比度灵敏度.
- 对比度的敏感性被评估为有或没有对比度降低.
主要成果:
- 关闭通路的响应明显高于在线通路的响应 (p < 0.0001).
- 与非近视患者相比,近视患者的对比敏感性普遍较低 (p = 0.05).
- 减少对比度并没有显著改变这些观察到的差异 (p > 0.05).
结论:
- 在近视和非近视之间存在视网膜ON/OFF信号处理的感知差异.
- 对比度降低对这些差异的影响并不支持它所提出的抑制近视发展的机制.
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