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Updated: Jul 26, 2025

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关于异常性脑内高血压试验报告的共同设计和数据元素:系统性审查

Hassan Kobeissi1, Cem Bilgin, Sherief Ghozy

  • 1Departments of Radiology (HK, CB, SG, WB, RK, DFK), Ophthalmology (TX, JJC), and Neurologic Surgery (RK), Mayo Clinic, Rochester, Minnesota; Department of Radiology (GA), Massachusetts General Hospital, Boston, Massachusetts; Nested Knowledge (JT, NH, RT, KMK), St Paul, Minnesota; Department of Neurology (AS), University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, United Kingdom; Translational Brain Science (AS, SPM), Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom; and Birmingham Neuro-Ophthalmology (SPM), University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, United Kingdom.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
|June 21, 2023
PubMed
概括

异形性内高血压 (IIH) 试验缺乏一致的设计和数据元素,阻碍了未来的研究综合. 建立关于试验设计的共识对于推进患者护理和IIH研究中的有效元分析至关重要.

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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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