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Updated: Jul 30, 2026

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一种可通过超声波激活的原药,用于超声波敏感化疗

Gongyuan Liu1,2, Yachao Zhang3, Houzong Yao1,2

  • 1Department of Chemistry, City University of Hong Kong, Hong Kong SAR, P.R. China.

Science advances
|June 21, 2023
PubMed
概括

超声波激活的氨酸原药通过破坏线粒体DNA有效地向深层瘤. 这种声敏化疗方法在癌症治疗中提供了卓越的疗效和生物安全性.

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Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...