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Updated: Jul 26, 2025

In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation
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H/ACA snRNP依赖的核糖体生物发生调节了多重氨酸蛋白的翻译

Shane M Breznak1, Yingshi Peng2, Limin Deng1,3

  • 1Department of Biological Sciences, RNA Institute, University at Albany, 1400 Washington Avenue, LSRB 2033D, Albany, NY 12222, USA.

Science advances
|June 21, 2023
PubMed
概括

干细胞的分化依赖于核糖体生物发生和翻译. 这项研究揭示了H/ACA小核核糖核蛋白 (snRNP) 复合体选择性地转化CAG重复含有信使RNA,这对卵细胞特异性至关重要.

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