预防移民群体经验性抗生素治疗失败:根据感染风险进行查,而不是根据种族背景进行查
Steven L Taylor1, Lito E Papanicolas1, Erin Flynn2
1South Australian Health and Medical Research Institute, Adelaide, Australia; College of Medicine and Public Health, Flinders University, Adelaide, Australia.
概括
多种耐药生物 (MDROs) 构成全球健康风险. 从高发病率地区前往低发病率地区的个人面临更高的治疗失败风险,需要积极的查策略.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 多药耐药生物体 (MDROs) 构成重大国际健康威胁,低收入和中等收入国家因滥用抗生素和卫生设施不足而加剧.
- MDROs的传播是一个全球性问题,通常被认为是对发达国家的威胁,忽视了来自高流行地区的旅行者面临的风险.
- 从MDRO患病率高的地区迁移到具有有效标准治疗的地区的个人,患抗生素治疗失败的风险增加.
研究的目的:
- 突出在不同MDRO流行地区之间移动的个体中传播细菌感染的治疗结果差.
- 建议修订MDRO选策略,重点关注未来的风险,而不是过去的收购,避免污名化.
- 提倡在高风险医疗事件发生之前进行预防性查,以改善患者的治疗结果并保护弱势群体.
主要方法:
- 这一观点分析了MDRO患病率对移动人口治疗结果的影响.
- 它讨论了当前查方法的局限性,并提出了基于未来风险评估的替代策略.
- 作者主张将查重点从地理来源转移到传播感染的个人风险因素.
主要成果:
- 从高MDRO流行地区前往低流行地区的个人经历传播细菌感染的较差结果.
- 目前的查方法风险是污名化移动人口,因为他们专注于过去的暴露.
- 积极的查方法,在高风险的医疗干预之前针对个体,可以减轻治疗失败.
结论:
- 对多种耐药生物体的查应基于个体未来传播感染的风险,而不是其原产地区.
- 在分娩,手术或免疫抑制前进行主动查可以显著减少抗生素治疗失败.
- 实施基于风险的查策略将改善患者的治疗结果,并防止移民人口的边缘化.
关键词:
抗生素耐药性 抗生素耐药性细菌病是什么意思 细菌病是什么意思扩展光谱β-lactamases是一种扩展光谱β-lactamases.微生物组是一个微生物组.抵抗力 抵抗力 抵抗力败血症 这是一种败血症.更多相关视频
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