生物进化需要一个新兴的,自我组织的原则
Olen R Brown1, David A Hullender2
1Emeritus of Biomedical Sciences, at the University of Missouri, Columbia, MO, USA.
Progress in biophysics and molecular biology
|June 21, 2023
概括
达尔文进化论努力解释诸如物种形成和坎布里亚爆炸之类的宏观进化事件. 一个拟议的生物电磁场可能会推动细胞的复杂自我组织,提供新的进化见解.
科学领域:
- 进化生物学 进化生物学
- 生物物理学的生物物理.
- 生物化学 生物化学
背景情况:
- 目前的进化模型,包括新达尔文主义,通过固定突变充分解释微观进化.
- 然而,这些模型在解释宏观进化现象方面面临挑战,例如在坎布里亚爆炸期间的物种化和快速多样化.
研究的目的:
- 批判性地评估达尔文进化论在解释宏观进化过渡过程中的基本局限性.
- 提出一个新的框架,包括自我组织和生物电磁原理,以解释复杂的生物结构和过程.
- 根据当前的机制和概率评估,强调进化途径的不太可能性.
主要方法:
- 透视性审查分析现有的进化理论及其解释性差距.
- 检查特定的复杂分子组合 (例如,核糖体,ATP合成酶) 作为自我组织的案例研究.
- 概率模型用于评估需要多个遗传变化的进化事件的可能性.
主要成果:
- 固定的突变和"最适者生存"不足以解释宏观进化,物种化或主要身体计划的起源.
- 需要大量遗传变化的进化事件的概率非常低.
- 复杂的细胞自我组织,以核糖体和ATP合成酶组装为例,表明了超出当前进化理解的机制.
结论:
- 建议生物电磁场/原理在活细胞中出现,以控制自我组织和复杂分子机械的合成.
- 这一新兴的原理为目前达尔文进化论无法解释的现象提供了潜在的解释.
- 物理和数学与生物学的更大整合,有专门的资金,对于推进进化理解和医学应用至关重要.
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