乙原和乙生成用于生物合成气价值化
Ji-Yeon Kim1, Mungyu Lee1, Soyoung Oh2
1School of Earth Sciences and Environmental Engineering, Gwangju Institute of Science and Technology, 123 Cheomdan-gwagiro, Buk-gu, Gwangju 61005, Republic of Korea; Research Center for Innovative Energy and Carbon Optimized Synthesis for Chemicals (inn-ECOSysChem), Gwangju Institute of Science and Technology, 123 Cheomdan-gwagiro, Buk-gu, Gwangju 61005, Republic of Korea.
Bioresource technology
|June 21, 2023
概括
使用乙酸原的合成气的生物转化为热化学转化提供了一种选择性,温和的替代方案. 提高生物催化剂和上游过程,比如使用Eubacterium limosum,可以提高合成气价值化的经济可行性.
科学领域:
- 生物技术和工业微生物学
- 化学工程是化学工程的重要组成部分.
- 合成生物学 合成生物学
背景情况:
- 通过 (同类) 乙原体进行合成气的生物转化,由于具有更高的选择性和更温和的条件,为热化学方法提供了一个有希望的替代方案.
- 目前的工艺在中游工程和下游净化 (TRL) 中表现出色,但上游生物催化剂的限制阻碍了经济可行性.
- 森林-Ljungdahl路径 (WLP) 是生物合成气利用的核心,涉及复杂的氧化还原平衡和ATP生成.
研究的目的:
- 对Wood-Ljungdahl路径进行综合气生物转换的审查.
- 探索在上游阶段增强生物催化剂选择的战略.
- 确定工业合成气发酵和利用的未来方向.
主要方法:
- 专注于木-Ljungdahl通路 (WLP) 机制,包括氧化还原平衡和ATP生成.
- 审查特定的生物催化剂,如Eubacterium limosum,用于合成气的价值化.
- 分析生产高降解化学品的策略,包括流量控制,混合种植和混合培养.
主要成果:
- 菌和其他特定的生物催化剂显示出有利的合成气价值化潜力.
- 诸如流量控制,混合种植和混合培养等策略可以用于有利于生产高度减少的化学物质.
- 世界生产计划为微生物合成气转化提供了一个强大的框架.
结论:
- 优化上游生物催化是提高合成气生物转化经济可行性的关键.
- 针对性地使用特定的微生物和种植策略可以增强从合成气中生产有价值的化学物质.
- 对工业合成气发酵的进一步研究具有可持续化学生产的巨大潜力.
相关概念视频
Fates of Pyruvate
8.7K
Pyruvate is the end product of glycolysis, where glucose is oxidized to pyruvate, simultaneously reducing NAD+ to NADH. Two molecules of ATP are also produced by substrate-level phosphorylation.
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
8.7K
Microbial Fermentation
88
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
88
Respiration Pathways
51
Cellular respiration is a fundamental metabolic process that enables organisms to generate energy from organic molecules. One of its central pathways is the tricarboxylic acid (TCA) cycle, also known as the Krebs cycle, which plays a crucial role in energy production and biosynthetic processes.Conversion of Pyruvate to Acetyl-CoAThe pyruvate generated from glycolysis undergoes oxidative decarboxylation by the pyruvate dehydrogenase complex, producing acetyl-CoA, one molecule of NADH, and one...
51
Products of the Citric Acid Cycle
99.2K
The cells of most organisms—including plants and animals—obtain usable energy through aerobic respiration, the oxygen-requiring version of cellular respiration. Aerobic respiration consists of four major stages: glycolysis, pyruvate oxidation, the citric acid cycle, and oxidative phosphorylation. The third major stage, the citric acid cycle, is also known as the Krebs cycle or tricarboxylic acid (TCA) cycle.
99.2K
Fermentation
115.8K
Most eukaryotic organisms require oxygen to survive and function adequately. Such organisms produce large amounts of energy during aerobic respiration by metabolizing glucose and oxygen into carbon dioxide and water. However, most eukaryotes can generate some energy in the absence of oxygen by anaerobic metabolism.
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
115.8K
Glycolysis
60
Glycolysis, the Embden-Meyerhof pathway, is a central metabolic pathway involved in glucose catabolism. It is highly conserved across most organisms, reflecting its fundamental role in cellular energy production. This process occurs in the cytoplasm and can function both in the presence and absence of oxygen, making it versatile for various organisms and environmental conditions.Stages of GlycolysisGlycolysis is a ten-step pathway that converts glucose into pyruvate, generating a net gain of...
60


