35岁及以上妇女因更年期而使用大麻:加拿大阿尔伯塔省关于使用模式和观念的横截面调查
Katherine Babyn1, Sue Ross2, Mark Makowsky1
1Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.
BMJ open
|June 21, 2023
概括
加拿大阿尔伯塔省的许多女性使用大麻治疗更年期症状,如睡眠和焦虑. 超过75%的现有用户使用大麻是出于医疗原因,发现它有助于缓解症状.
科学领域:
- 生殖医学和更年期
- 大麻研究和治疗方法.
- 公共卫生和流行病学
背景情况:
- 加拿大大麻使用增加2018年娱乐合法化后的加拿大大麻使用增加.
- 对更年期症状管理的替代疗法越来越感兴趣.
- 关于更年期妇女使用大麻模式和认知的有限数据.
研究的目的:
- 调查大麻使用模式对更年期症状的研究.
- 探索女性对大麻作为更年期治疗的看法.
- 在这个人口群体中确定与大麻使用相关的因素.
主要方法:
- 在加拿大阿尔伯塔省,对35岁以上的女性进行了横截面,基于网络的调查.
- 通过社交媒体平台 (Facebook,Instagram,Twitter) 进行招聘.
- 收集关于人口统计,更年期状态,症状和大麻使用观念的数据;使用描述性统计和后勤回归分析.
主要成果:
- 在1485名被分析的参与者中,34%目前使用大麻;66%以前使用过大麻.
- 超过75%的现有用户使用大麻用于医疗目的,主要用于睡眠 (65%),焦虑 (45%) 和疼痛 (33%).
- 74%的现有使用者发现大麻对症状有帮助;使用者更有可能报告更年期症状.
结论:
- 一些女性正在使用大麻来管理与更年期相关的症状.
- 为了评估大麻对更年期的安全性和有效性,需要进一步的研究.
- 需要为妇女开发有关大麻和更年期的临床资源.
相关概念视频
Menopause
208
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
208
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
326
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Two synthetic agonists of THC,...
326
Hormonal Regulation of the Menstrual Cycle
461
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
461
Altered States of Awareness
254
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
254
Stress Prevention and Stress Management Techniques IV
49
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
49
Psychoneuroimmunology: Diabetes and Cancer
49
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
49


