振动性定位治疗设备在定位阻塞性睡眠呼吸暂停患者的有效性:系统性审查和元分析
Abdullah S ALQarni1,2,3, Chris D Turnbull4,5,6, Mary J Morrell7
1National Heart and Lung Institute, Imperial College London, London, UK asalqarni@iau.edu.sa.
Thorax
|June 21, 2023
概括
振动性定位治疗有效地降低了位置阻断性睡眠呼吸暂停的无呼吸失眠指数和卧卧姿的时间. 需要进一步的研究来评估长期以患者为中心的结果.
科学领域:
- 睡眠医学 睡眠医学
- 医疗器械 医疗器械
- 呼吸系统医学 呼吸系统医学
背景情况:
- 定位阻塞性睡眠呼吸暂停 (POSA) 是睡眠呼吸障碍的一种亚型.
- 振动定位疗法 (PT) 为POSA提供了一种新的治疗方法.
研究的目的:
- 评估振动性PT在降低POSA患者的无呼吸失眠指数 (AHI) 和卧床睡眠时间 (%Tsupine) 的有效性.
- 评估振动性PT对白天嗜睡,生活质量和睡眠质量的影响.
主要方法:
- 随机对照试验 (RCT) 和队列研究的系统审查和元分析.
- 在MEDLINE,CENTRAL和Embase数据库中进行搜索,截至2022年10月.
- 包括18项研究 (10项RCT,8项队列研究) 来自1119项已识别的研究.
主要成果:
- 振动性PT显著降低了AHI (平均差异-9.19事件/小时) 和%Tsupine (平均差异-32.79%).
- 百分比下降的是43%的AHI和70%的%Tsupine.
- 包括白天嗜睡和生活质量在内的次要结局显示出最小的变化,随访时间很短.
结论:
- 振动性PT有效降低POSA患者的关键目标指标 (AHI和%Tsupine).
- 对睡眠质量和白天嗜睡等主观结果的影响是有限的.
- 建议进行进一步的长期随访研究,以确定对以患者为中心的结果的长期影响.
关键词:
睡眠呼吸暂停 睡眠呼吸暂停相关概念视频
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