通过皮肤关闭左前庭尾后的抗血栓治疗方案 - 一个真实世界的研究
Satoko Ryuzaki1, Yusuke Kondo1, Miyo Nakano1
1Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine.
概括
在左心房附带关闭 (LAAC) 后修改的抗血栓治疗在高风险患者中是安全有效的. 与设备相关的血栓形成减少了修改后的治疗方案,并没有增加重大出血事件.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 血栓形成研究研究
背景情况:
- 在高风险出血患者中,左心房关闭后的抗血栓治疗 (LAAC) 是有争议的.
- 关于LAAC结果的现实数据对于优化患者管理至关重要.
研究的目的:
- 评估不同抗血栓治疗方案在高出血风险患者的LAAC后的临床结果.
- 评估LAAC后修改的抗血栓策略的安全性和有效性.
主要方法:
- 分析了2020年1月至2022年6月间连续接受LAAC治疗的74名患者.
- 根据出血风险或临床事件,患者被分配到三种抗血栓治疗方案之一.
- 治疗方案包括标准方法,降低剂量抗血小板策略和在特定情况下长期使用抗血小板药物.
主要成果:
- 98.6%的LAAC程序是成功的.
- 与设备相关的血栓形成发生在标准治疗方案 (治疗方案1) 的13%患者中,但在修改方案 (治疗方案2和3) 中没有出现 (P=0.0257).
- 在这三种疗法中,主要出血事件发生率没有显著差异 (P=0.53).
结论:
- 在LAAC后修改的抗血栓治疗方案可以在高风险患者中安全实施.
- 这些修改后的策略可以减少与设备相关的血栓发生率,而不会增加出血风险.
相关概念视频
Venous Thrombosis III: Interprofessional Care
11
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
11
Anticoagulant Drugs: Low-Molecular-Weight Heparins
763
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
763
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
14
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
14
Acute Coronary Syndrome IV: Interprofessional Care
13
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
13
Peripheral Artery Disease III: Interprofessional Care
13
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
13


