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Author Spotlight: Exploring the Role of FAM83A in Cervical Cancer
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在子宫内膜癌中,FBXO7是一种瘤抑制剂,抑制INF2相关的线粒体分裂

Hui Zhang1,2, Yiting Zhao1,2, Jie Wang2

  • 1Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Ningbo University, Ningbo, Zhejiang, 315211, China.

Cell death & disease
|June 21, 2023
PubMed
概括

FBXO7通过降解INF2,抑制线粒体分裂,在子宫内膜癌 (ECa) 中起瘤抑制作用. 在FBXO7中的突变破坏了这一点,促进了ECa. 针对INF2-DRP1轴为ECa提供了新的治疗策略.

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