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Updated: Jul 26, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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PD-1 保持 CD8 T 细胞对皮肤新抗原的耐受性

Martina Damo1, Noah I Hornick1,2, Aarthi Venkat3

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

Nature
|June 21, 2023
PubMed
概括

编程细胞死亡蛋白1 (PD-1) 通过调节自我反应的CD8T细胞来维持皮肤耐受性. 这可以防止组织损伤和与免疫相关的不良事件,支持外围T细胞耐受性的新模型.

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