感染后的功能性胃肠道疾病后的冠状病毒疾病-19:一个潜在的后续队列研究
Daya Zhang1, Chen Chen1, Yunqian Xie2,3
1Graduate School, Hainan Medical University, Haikou, 571199, China.
COVID-19 感染增加了在六个月内发展新的功能性胃肠道疾病 (FGID) 的风险. 在最初的COVID-19疾病期间的胃肠道症状是这些长期FGID的关键预测因素.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 已知急性胃肠道感染会导致后感染性刺激性肠综合征 (PI-IBS).
- 冠状病毒疾病 (COVID-19) 与持续的胃肠道问题有关.
- 了解COVID-19后的感染后功能性胃肠道疾病 (PI-FGID) 是至关重要的.
研究的目的:
- 为了前性地检查COVID-19患者PI-FGIDs的频率和频谱.
- 为了确定COVID-19后发展PI-FGIDs的风险因素.
- 为了比较COVID-19幸存者与健康对照者的PI-FGID发病率.
主要方法:
- 使用已验证的罗马III和罗马IV问卷进行评估.
- 在前性研究中包括190名COVID-19患者和160名健康对照.
- 在感染/注册后的1,3个月和6个月内跟踪参与者.
主要成果:
- 在COVID-19患者 (8.9%) 和对照组 (3.1%) 中,FGID发病率在6个月后显著增加.
- 观察到的特定FGID包括刺激性肠综合征,功能性消化不良,腹和便秘.
- 在COVID-19开始时,胃肠道症状被确定为FGIDs发展的独立风险因素.
结论:
- COVID-19感染与六个月后新发PI-FGID的发病率增加有关.
- 在COVID-19期间早期的胃肠道症状是后续FGID的重要预测因素.
- 这凸显了COVID-19后监测肠道肠道健康的重要性.
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