在非功能性下垂体腺瘤患者的术后中长期内分泌结果-机器学习分析分析
Ziad Hussein1,2,3, Robert W Slack4,5, Hani J Marcus4,6
1Department of Diabetes & Endocrinology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S10 2JF, UK.
Cancers
|June 22, 2023
概括
机器学习模型可以预测非功能性垂体腺瘤 (NFPA) 手术后的长期下垂体病变. 这些模型,特别是支持矢量机,比预测内分泌结果的传统方法提供了更好的准确性.
科学领域:
- 内分泌学 在内分泌学.
- 神经外科 神经外科
- 人工智能的人工智能
背景情况:
- 下垂体腺瘤手术的结果各不相同.
- 预测术后内分泌功能障碍是一个挑战.
研究的目的:
- 使用机器学习 (ML) 预测非功能性垂体腺瘤 (NFPA) 患者的中长期和长期手术后垂体缺陷症.
主要方法:
- 利用了383名NFPA患者的数据 (手术+/-放射治疗,6个月-15年的随访).
- 将ML模型 (KNN,SVM,决策树) 与非参数统计建模进行比较.
- 评估了预测准确性和AUC-ROC用于泛阴垂体病.
主要成果:
- 机器学习模型的性能优于传统方法 (平均精度:0.89与非参数).
- SVM获得了最高的性能 (平均精度:0.94,AUC-ROC:0.88).
- 手术前内分泌功能,1年后的结果,年龄,瘤体积和放射治疗使用是关键预测因素.
结论:
- ML模型显示,在预测NFPA患者手术后的下垂体病的过程中,具有显著的潜力.
- SVM显示出对内分泌结果的卓越预测能力.
- 未来的研究应该整合多模式数据,以提高预测准确度.
关键词:
决策树是一个决策树.这是一种hypopituitarism.这里是KNN.逻辑回归的逻辑回归机器学习是机器学习.功能不良的垂体腺瘤这是一种泛hypopituitarism.这就是SVM svm.更多相关视频
12:34Two-dimensional Gel Electrophoresis Coupled with Mass Spectrometry Methods for an Analysis of Human Pituitary Adenoma Tissue Proteome
Published on: April 2, 2018
13.5K
07:15Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
Published on: August 16, 2020
6.9K
相关概念视频
Hormones of the Pituitary Gland
6.8K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
6.8K
The Pituitary Gland
6.9K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
6.9K
