可食用草药作为治疗睡眠障碍常见药物的替代品:一篇评论文章
Azar Hosseini1, Leila Mobasheri1, Hassan Rakhshandeh1
1Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad Iran.
Current neuropharmacology
|June 22, 2023
概括
研究人员探索了治疗失眠的波斯草药,发现与二胺受体相互作用的天然化合物,为传统睡眠药物提供了更安全的替代品.
科学领域:
- 药理学 药理学是指药理学的学科.
- 民族植物学 民族植物学
- 神经科学是一个神经科学.
背景情况:
- 失眠是一种睡眠障碍,其特点是难以入睡,保持睡眠或睡眠质量差,导致白天睡眠受损.
- 目前的失眠治疗方法,如二类药物,有局限性,包括耐受性和依赖性,需要寻找更安全的替代品.
- 自然产品,特别是药草,历史上一直是治疗各种疾病的治疗剂的来源,包括睡眠障碍.
研究的目的:
- 研究精选的波斯草药在治疗失眠方面的疗效.
- 探索这些天然产品作为传统失眠药物的替代品的潜力.
- 确定这些草药在促进睡眠中的活性化合物和作用机制.
主要方法:
- 进行了一项临床试验和体内研究.
- 这项研究检查了包括Artemisia annua,Salvia reuterana,Viola tricolor,Passiflora incarnata,和Capparis spinose在内的波斯草药.
- 分析的重点是草本提取物和分数,特别是n-butanol分数,以及它们与二胺受体的相互作用.
主要成果:
- 某些草本提取物和分离物,特别是n-butanol分离物,表现出催眠性质.
- 发现这些天然化合物会影响二胺受体,类似于一些常规的睡眠辅助剂.
- 类化合物,糖化物,黄类化合物,沙素和素被确定为促进平静和促进睡眠的关键化合物.
结论:
- 波斯草药显示出治疗失眠的巨大潜力.
- 这些草药中的天然化合物为开发具有潜在较少副作用的新失眠疗法提供了有希望的途径.
- 对这些民族植物药物的进一步研究可能会导致新,安全和有效的睡眠辅助剂.
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