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通过人工智能揭示的男性具有detrusor低活性的尿液流量测量模式的特征
Yoshihisa Matsukawa1, Yoshitaka Kameya2, Tomoichi Takahashi3
1Department of Urology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
概括
尿液流量计 (UFM) 的第一个峰值流量参数,特别是第一个峰值流量与最大流量 (Qmax) 的比率,可以准确地诊断下游泌尿道症状 (LUTS) 的男性的排尿器低活性 (DU). 这有助于区分DU与膀输出阻塞 (BOO).
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医学诊断 医学诊断 医学诊断
- 人工智能在医学中的应用
背景情况:
- 男性的下泌尿道症状 (LUTS) 往往源于排尿器低活性 (DU) 或膀出口阻塞 (BOO).
- 精确区分DU和BOO对于有效治疗至关重要,但尿液流量计 (UFM) 的解释可能是复杂的.
研究的目的:
- 调查男性患有DU的UFM参数的诊断特征.
- 使用人工智能 (AI) 算法来识别区分DU和BOO的关键UFM特征.
主要方法:
- 在266名LUT的男性中,比较了四个UFM参数 (第一个峰值流量,第一个峰值的时间,第一个峰值的梯度,第一个峰值流量与Qmax的比率).
- 利用多变量和接收器操作特征 (ROC) 曲线分析来确定DU的预测UFM参数.
- 定义的DU是膀收缩指数<100和BOO指数<40.
主要成果:
- 大多数第一峰流UFM参数在DU组显著较低.
- 较低的第一个峰值流速和较低的第一个峰值流速与Qmax的比率是 DU 的显著预测因素.
- 第一次峰值流速与Qmax的比率显示出高的诊断准确性 (AUC 0.848,灵敏度 76%,在切线值为0.8的特异性为83%)
结论:
- UFM的第一个峰值流量参数,特别是第一个峰值流速与Qmax的比率,在诊断LUTS男性的DU时提供了高准确度.
- 这些发现支持使用特定的UFM指标来区分DU和BOO.
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