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Updated: Jul 26, 2025

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
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癌症相关纤维细胞在非小细胞肺癌中的免疫调节功能

Hyewon Lee1, Mina Hwang2, Seonae Jang2

  • 1Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul, Republic of Korea.

Tuberculosis and respiratory diseases
|June 22, 2023
PubMed
概括

非小细胞肺癌 (NSCLC) 的癌症相关纤维细胞 (CAF) 抑制T细胞功能,促进免疫逃避. 循环氧化酶-2 (COX2) 抑制剂可以减轻这种免疫抑制作用,恢复T细胞活性.

关键词:
COX2二氧化碳的使用.癌症相关的纤维细胞.免疫抑制 免疫抑制在PD-L1中.原发性肺癌是一种主要的肺癌.

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