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Updated: Jul 26, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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通过对EREG/EGFR/mTOR复合体1信号通路的下调,ELF3抑制了胆囊癌的发展

Takeharu Nakamura1, Yoshihiro Nishikawa1,2, Masahiro Shiokawa1

  • 1Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

The Journal of pathology
|June 22, 2023
PubMed
概括

类似于E74的ETS转录因子3 (ELF3) 的功能丧失突变在胆囊癌 (GBC) 中很常见. 通过降低EREG/EGFR/mTORC1信号调节,ELF3抑制GBC,这表明EGFR/mTORC1抑制是潜在的治疗方法.

关键词:
欧洲农业基金会 (EGFR) 是一个基金.ELF3 ELF3 在线播放欧洲经济论坛 欧洲经济论坛 EREG EREG胆囊癌是一种胆囊癌.mTOR复合体 1 1 的情况.

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