在双抗血小板治疗的患者中可以安全地进行内镜乳头气球扩张:试点研究
Sakue Masuda1, Ryuhei Jinushi2, Kazuya Koizumi3
1Department of Gastroenterology, Shonan Kamakura General Hospital, Kanagawa, Japan. sakue.masuda@tokushukai.jp.
Journal of gastrointestinal and liver diseases : JGLD
|June 22, 2023
概括
透视乳头乳头气球扩张 (EPBD) 对于接受双抗血小板治疗的患者来说是安全的,没有显示出增加的出血风险. 这种微创手术为高危人群的普通胆道结石切除提供了一个可行的选择.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
背景情况:
- 内皮质气球扩张 (EPBD) 是一种低风险的替代方案,用于内皮质扩张的内皮质瘤切除术.
- 指导方针建议在内镜缩术期间将双重抗血小板治疗减少到单一治疗.
- 缺乏关于EPBD对双重抗血小板治疗患者出血风险的影响的证据.
研究的目的:
- 在接受双抗血小板治疗的患者中调查EPBD的安全性.
- 在服用联合抗血小板剂的患者中评估与EPBD相关的出血风险.
主要方法:
- 对31名因常见胆道结石而接受EPBD患者的回顾性研究.
- 患者接受了双重或单一的抗血小板治疗.
- 双抗血小板组包括没有或短暂抗血小板戒断期的患者.
主要成果:
- 在接受EPBD的患者中没有观察到出血事件,即使是那些接受双重抗血小板治疗的患者.
- 两组之间血红蛋白水平或ERCP后胰腺炎发病率没有显著差异.
- 诺皮里丁是双重治疗组中使用的抗血小板药物之一.
结论:
- 在接受双重抗血小板治疗的患者中,可以安全地进行EPBD,而不会增加出血风险.
- 在需要双重抗血小板治疗的患者中,EPBD为常见的胆道结石提供了安全的内镜干预.
- 建议进行进一步的前性研究来验证这些发现.
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