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Updated: Jul 26, 2025

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
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免疫检查点活动调节多囊病的进展

Emily K Kleczko1, Dustin T Nguyen1, Kenneth H Marsh1

  • 1Department of Medicine, Division of Renal Diseases and Hypertension.

JCI insight
|June 22, 2023
PubMed
概括

针对PD-1和CTLA-4的双免疫检查点阻塞,通过增强CD8+T细胞活性,改善了自体主导多囊性病 (ADPKD) 模型的结果.

关键词:
适应性免疫是一种适应性免疫.单一性疾病是一种单一性疾病.腎臟病學 (nephrology) 是一種醫學專業.

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