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在水幽灵中基于MRI相位信号的质子束可视化对比机制的研究

Juliane Schieferecke^1,2, Sebastian Gantz^1,2,3, Aswin Hoffmann^1,2,3

¹OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

Magnetic resonance in medicine

|June 22, 2023

概括

对质子束的MRI相位信号可视化是使用对流引起的对比度可行的. 这种方法在MR集成质子束疗法中显示出质量保证的希望,尽管直接组织应用有限.

科学领域:

医学物理医学物理
磁共振成像是一种磁共振成像技术.
辐射瘤学辐射瘤学

背景情况:

使用MRI大小信号的质子束可视化灵敏度低,仅限于水幽灵.
目前的方法阻碍了MR集成质子束疗法的体内适用性.

研究的目的:

调查MRI相位信号机制,以增强质子束可视化.
评估对比机制,以提高对组织材料的灵敏度和适用性.

主要方法:

实验对水幽灵的特征,时间和成像参数进行了变化,使用飞行时间血管学脉冲序列.
使用速度编码来量化光束诱导的对流量,并评估其对MRI相位信号的影响.

主要成果:

基于MRI相位信号的质子束可视化被证明是可行的.
阶段对比主要是由光束诱导的浮力对流 (毫米/秒范围) 驱动的;磁场扰动和易感性变化不是重要的因素.
速度编码增强了检测灵敏度.

结论:

由于流量受限,对流依赖的MRI相位对比方法不太可能转移到隔间组织.
强大的速度编码脉冲序列显示了MR集成质子束疗法的几何质量保证潜力.

关键词:

电流对流是指对流的对流.在内射射线的MRI.阶段差成像成像是相差的成像.质子束可视化可视化质子疗法是一种质子疗法.速度编码的速度编码.

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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...