非功能性垂体腺瘤的自然史:来自英国非功能性垂体腺瘤联盟的结果
Ross Hamblin1,2,3, Athanasios Fountas1,2,3, Kirstie Lithgow1,2,3
1Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
European journal of endocrinology
|June 22, 2023
概括
通过延迟成像,可以安全地管理非功能性垂体微腺瘤 (微NFPA) 的监测. 增长的低概率和罕见的垂体下垂体支持这些垂体瘤的不那么密集的随访策略.
科学领域:
- 内分泌学 在内分泌学.
- 神经外科 神经外科
- 在瘤学瘤学.
背景情况:
- 对非功能性垂体小腺瘤 (micro-NFPAs) 的最佳监测策略仍未确定.
- 了解微型NFPAs的自然史对于指导患者管理和随访协议至关重要.
研究的目的:
- 为了研究微型NFPAs的自然史.
- 为微型NFPAs的监测提供基于证据的建议.
- 为临床决策提供有关随访频率和荷尔蒙评估的信息.
主要方法:
- 进行了一项多中心的回顾性队列研究.
- 分析了来自23个内分泌部门的459名微型NFPA患者的数据.
- 在2008年至2021年期间收集了临床,成像 (MRI) 和荷尔蒙数据.
主要成果:
- 微型NFPA生长的累积概率在3年后为7.8%,在5年后为14.5%.
- 瘤减少发生在14.1%的3年和21.3%的5年.
- 只有0.6%的患者出现了新的下垂体病,主要是在瘤进展为宏腺瘤后.
结论:
- 微型NFPA的生长不常见,新型下垂体病的发展也很罕见.
- 将第一个随访MRI推迟到3年是一个安全的监测方法.
- 如果没有瘤生长或临床变化,可以避免进行激素再评估.
关键词:
腺瘤腺瘤是一种偶尔发生的瘤.自然历史,自然历史.不起作用的非功能.pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary 下垂体 下垂体 下垂体 下垂体 下垂体 下垂体 下垂体 下垂体更多相关视频
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