在阿尔法-1抗素缺乏症患者的身体活动,运动能力和久坐行为:一个范围审查
Orlagh O'Shea1, Saidhbhe Casey1, Ciaran Giblin1
1School of Physiotherapy, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin 2, Ireland.
概括
在阿尔法-1抗素缺乏症 (AATD) 中对身体活动 (PA) 的研究是有限的. 研究主要评估了运动能力,很少有干预措施针对日常PA或测量COPD风险人群中的久坐行为 (SB).
科学领域:
- 肺部医学 肺部医学
- 遗传学 是一个遗传学.
- 运动生理学 运动生理学
背景情况:
- 阿尔法-1抗素缺乏症 (AATD) 是一种遗传性疾病,增加慢性阻塞性肺病 (COPD) 的风险.
- 身体活动 (PA) 对于管理COPD等慢性疾病至关重要.
- 目前对AATD患者的PA和久坐行为 (SB) 缺乏理解.
研究的目的:
- 系统地审查和绘制有关测量和改善AATD患者的PA,SB和运动的现有研究.
- 识别AATD中有关PA和SB的当前研究环境中的差距.
主要方法:
- 在CINAHL,Medline,EMBASE和临床试验数据库中对2021年发表的研究进行了全面的文献搜索.
- 关键词包括"身体活动"",AATD"",运动"和"久坐行为",以及同义词,由布尔运算符连接在一起.
- 总共有360个记录被确定,最终包括在审查中的是37项研究.
主要成果:
- 所有37项包括的研究都使用各种客观措施 (例如,六分钟步行测试,增量穿步行测试,CPET) 和一些自我报告的方法来评估运动能力.
- 只有一个研究研究了强化健身干预对每日血压的影响,另一个研究报告了运动干预研究中的基线血压.
- 没有研究专注于测量或干预AATD人群中的久坐行为 (SB).
结论:
- 对PA的评估及其在AATD中作为干预措施的使用是非常有限的.
- 没有专门针对AATD患者的久坐行为研究.
- 未来的研究应优先考虑对PA和SB的客观测量,并制定干预措施,以促进这种易受影响的人群的体力活动.
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