在白内障手术后的内皮细胞损失,使用连续曲线性囊或精确脉冲囊切除术
Mark C Vital1, Kevin Y Jong1, Clarise E Trinh1
1Houston Eye Associates, Houston, TX, USA.
Clinical ophthalmology (Auckland, N.Z.)
|June 22, 2023
概括
在白内障手术后,连续曲线性囊复合 (CCC) 和精密脉冲囊切除 (PPC) 在内皮细胞密度,六角细胞和细胞大小变化方面表现出类似的结果. PPC不会增加内皮细胞损失.
科学领域:
- 眼科医生 眼科 眼科
- 角质科学 角质科学
- 白内障手术技术 白内障手术技术
背景情况:
- 白内障手术涉及囊切除,这是影响角膜内皮细胞的关键步骤.
- 连续曲线状囊 (CCC) 是一种标准的手动技术.
- 精密脉冲囊切除术 (PPC) 是囊切除术的一个自动化替代方案.
研究的目的:
- 为了比较内皮细胞密度 (ECD),六角细胞百分比 (%Hex) 和白内障手术后的细胞大小变化 (CV),使用连续曲线性囊复合 (CCC) 与精确脉冲囊切除术 (PPC).
- 评估PPC在化过程中保护角膜内皮细胞的安全性和有效性.
主要方法:
- 67名受试者被随机分配,接受CCC或PPC的白内障手术.
- 镜像显微镜在手术前和手术后1个月和3个月进行.
- ECD,%Hex和CV被一个独立的阅读中心掩盖分析.
主要成果:
- 三个月后,CCC (11.7%) 和PPC (12.4%) 组之间的平均百分比ECD损失没有显著差异 (P=0.815).
- 平均%Hex和CV在1个月和3个月后也显示CCC和PPC组之间没有显著差异.
- 与CCC相比,PPC没有导致内皮细胞损失增加.
结论:
- 精密脉冲囊切除术 (PPC) 是在白内障手术期间进行囊切除术的连续曲线性囊切除术 (CCC) 的安全替代方案.
- PPC不会导致额外的内皮细胞损失,超过与化相关的预期量.
- 在手术后,这两种技术都保持了类似的角膜内皮细胞健康.
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