牙周炎感染是否是血栓塞栓性疾病的危险因素? 一个系统的审查
Oinam Monica Devi1, Jyoti Gupta1, Gurparkash Singh Chahal1
1Department of Periodontology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India.
Journal of Indian Society of Periodontology
|June 22, 2023
概括
牙周病可能会增加静脉血栓塞栓症 (VTE) 的风险,这是一种包括肺栓塞 (PE) 在内的严重疾病. 牙科治疗和抗微生物药物可以消除与牙周炎相关的VTE症状,但需要更多的研究.
科学领域:
- 口腔健康 口腔健康
- 心血管健康 心血管健康
- 传染性疾病 传染性疾病
背景情况:
- 静脉血栓塞栓症 (VTE),包括肺栓塞 (PE) 和深静脉血栓,是一个日益严重的健康问题,具有显著的死亡率,发病率和经济影响.
- 牙周炎是一种口腔感染,可以通过全身炎症,高凝固性和血小板聚合来提高静脉瘤风险.
研究的目的:
- 系统地审查有关牙周炎感染与血栓塞栓性疾病风险之间的相关性现有证据.
主要方法:
- 在PubMed,Scopus和EMBASE数据库中对1967年至2020年12月发表的文章进行了全面的文献搜索.
- 包括的研究包括三个临床试验,两个病例系列和十个病例报告,进行了定性分析.
主要成果:
- 在牙周病和静脉血栓栓塞性疾病发生之间发现了统计学上显著的关联 (<0.010).
- 案例研究表明,在牙周炎的牙科和抗菌药物治疗后,败血性肺栓塞和症状的消失.
结论:
- 这一审查表明牙周病和血栓塞栓性疾病发病率之间存在潜在联系.
- 由于病例系列和报告占主导地位,目前的证据有限;需要强大的纵向研究来证实这一关联.
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