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Updated: Jul 26, 2025

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通过CRISPR在允许性细胞中进行传染性HIV颗粒的战略自我限制生产

Hong Liu1, Chen Chen1, Shuren Liao1

  • 1Center for Neurovirology and Gene Editing, Department of Microbiology, Immunology, and Inflammation, Lewis Katz School of Medicine at Temple University, 3500 N. Broad Street, 7th Floor, Philadelphia, PA 19140, USA.

Molecular therapy. Nucleic acids
|June 22, 2023
PubMed
概括

在HIV-1感染细胞中对曼诺西尔寡糖化糖酶 (MOGS) 的基因编辑产生非传染性病毒颗粒. 这种CRISPR-MOGS方法,结合向HIV-1 DNA,为HIV-1提供了潜在的治愈策略.

关键词:
基因编辑CRISPR基因编辑通过CRISPR预防病毒进入.艾滋病毒感染 艾滋病毒感染MT:RNA/DNA编辑 编辑结合基因编辑用于治愈艾滋病病毒.葡萄糖酶化是什么? 葡萄糖酶化是什么?曼诺西尔寡糖类糖酶 (MOGS)非传染性病毒生产非传染性病毒生产

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