Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

163
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
163
Intellectual Disability01:29

Intellectual Disability

120
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
120
Learning Disabilities01:25

Learning Disabilities

220
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
220
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

1.4K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
1.4K
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

133
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
133
Three Developmental Domains01:29

Three Developmental Domains

191
Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and...
191

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Caregiver-Associated Physical Activity Patterns, Dietary Behaviors and Interventional Beliefs in Individuals with Down Syndrome: Insights from a Large European Survey.

Nutrients·2026
Same author

Understanding Obesity in Individuals with Down Syndrome: Caregiver Perceptions, Awareness, and Motivation.

Nutrients·2026
Same author

Promoting Research Excellence in Down Syndrome: Proceedings of the 5th International Conference of the Trisomy 21 Research Society.

Neuromolecular medicine·2026
Same author

Retrotransposons as both "architects" and "saboteurs" in the nervous system.

Advances in genetics·2026
Same author

Integrating Genetic Variants and Expression Profiles of Pharmacogenes to Investigate Resistance to Antidepressant Treatment.

Medicina (Kaunas, Lithuania)·2026
Same author

Common pathogenic mechanisms in the hippocampus across neurodegenerative dementias: Alzheimer's disease, Down syndrome, and Parkinson's disease.

NPJ dementia·2026

相关实验视频

Updated: Jul 26, 2025

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
10:47

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

10.0K

神经发育障碍:2023年更新

Paulina Carriba1,2, Nicola Lorenzón1, Mara Dierssen1,3,2

  • 1Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.

Free neuropathology
|June 22, 2023
PubMed
概括

神经发育性疾病 (NDD) 的最新进展揭示了新的原因. 像人工智能和有机体这样的技术正在发现包括自闭症谱系障碍 (ASD) 和COVID-19神经效应在内的疾病的机制.

关键词:
CLIP:尾尾后期内部神经元原始体.中心体是中心体的组成部分.人类的有机体.MCD:皮层发育的形.SUDC:童年突然无法解释的死亡.压力颗粒是压力颗粒.

更多相关视频

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.1K
Author Spotlight: A Lightweight Drive Implant for Chronic Tetrode Recordings in Juvenile Mice
06:34

Author Spotlight: A Lightweight Drive Implant for Chronic Tetrode Recordings in Juvenile Mice

Published on: June 2, 2023

2.9K

相关实验视频

Last Updated: Jul 26, 2025

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
10:47

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

10.0K
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.1K
Author Spotlight: A Lightweight Drive Implant for Chronic Tetrode Recordings in Juvenile Mice
06:34

Author Spotlight: A Lightweight Drive Implant for Chronic Tetrode Recordings in Juvenile Mice

Published on: June 2, 2023

2.9K

科学领域:

  • 神经科学是一个神经科学.
  • 遗传学 是一个遗传学.
  • 发展生物学 发展生物学

背景情况:

  • 神经发育性疾病 (NDD) 是一个多样化的疾病群体,其来源各异.
  • 技术进步对于理解复杂的NDD病因至关重要.

研究的目的:

  • 突出最近的发现和NDDs在2022年报告的建议病因机制.
  • 展示新技术对NDD研究的影响.

主要方法:

  • 蛋白质组学和RNA测序用于分子分析.
  • 大脑器官模型用于研究神经发育.
  • 人工智能 (AI) 用于生物数据分析.

主要成果:

  • 中心细胞参与神经元迁移和周周结核异构.
  • 错误折叠的蛋白质积累与COVID-19的神经效应有关.
  • 改变皮层区域化被认为是自闭症谱系障碍 (ASD) 的机制.

结论:

  • 由于技术进步,对NDD病因的新见解正在出现.
  • 具体发现包括中枢细胞,蛋白质错折和NDDs中的皮质发育的作用.
  • 未来的研究方向包括研究压力颗粒放松调节,新的神经原始体,以及对NDD的改进诊断.