使用或不使用修改型甲状腺悬浮来治疗阻塞性睡眠呼吸暂停的乌帕拉托法林戈普拉斯蒂:一项随机临床试验
Zahra Eslami Panah1, Alireza Sharifi2, Sepideh Zoafa2
1Department of Otorhinolaryngology-Head and Neck Surgery, Tehran University of Medical Sciences, Tehran, Iran.
概括
添加修改后的甲状腺悬浮剂Uvulopalatopharyngoplasty与舌头底部射频显著改善了阻塞性睡眠呼吸暂停 (OSA) 患者的结果. 这种结合方法的成功率比单独的乌巴拉多法林戈普拉斯蒂更高.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 睡眠医学 睡眠医学
- 手术创新 在外科创新.
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 对健康构成重大风险.
- 外科手术的目的是改善气道的通透性.
- 结合舌根无线电频率 (TB-RF) 的乌vulopalatopharyngoplasty (UPPP) 是一个常见的治疗方法.
研究的目的:
- 为了比较UPPP+TB-RF与UPPP+改性甲状腺悬浮剂+TB-RF的疗效.
- 评估前舌底部肌肉悬浮对OSA治疗结果的影响.
- 评估手术成功率和各种患者报告和客观措施.
主要方法:
- 一项随机对照试验涉及48名OSA患者.
- 两个手术组:UPPP + 修改型甲状腺悬浮 + TB-RF与UPPP + TB-RF.
- 在手术前和后评估呼吸暂停-呼吸暂停指数 (AHI),氧和度,DISE,ESS,DSST,SSSS和T90.
主要成果:
- UPPP + 修改型甲状腺悬浮 + TB-RF 组显示出明显更好的 AHI 和 SSSS 评分 (P=0.010).
- 暂停组的成功率为75%,而UPPP+TB-RF组的成功率为41.7% (P=0.021).
- 在平均/最低O2和,ESS,DSST或T90.0中没有发现显著差异.
结论:
- 将修改后的甲状腺悬浮剂添加到UPPP和TB-RF中,可以提高OSA患者的外科治疗结果.
- 与单独使用TB-RF的UPPP相比,这种联合技术的成功率显著更高.
- 修改后的甲状腺悬浮液是提高OSA管理中UPPP疗效的宝贵补充剂.
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