饮食质量,植物性饮食,全身炎症和死亡风险之间的关联:NHANES的发现
Yoko Brigitte Wang1,2,3, Amanda J Page4,5, Tiffany K Gill6
1Vagal Afferent Research Group, School of Biomedicine, University of Adelaide, Adelaide, SA, Australia. yokobrigitte.wang@adelaide.edu.au.
更高的饮食质量和健康的植物性饮食 (PBD) 与较低的炎症有关,而不健康的PBD会增加炎症. 坚持饮食指南可能会降低与炎症相关的死亡率,特别是在肥胖的人群中.
科学领域:
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
- 预防慢性疾病 预防慢性疾病
背景情况:
- 系统性炎症是已知的死亡风险因素,特别是心血管疾病 (CVD) 和癌症.
- 饮食质量,植物性饮食 (PBD) 和与死亡率相关的炎症之间的相互作用,特别是在肥胖患者中,仍然未被充分探索.
研究的目的:
- 调查饮食质量 (健康饮食指数-2015;HEI-2015) 和各种植物性饮食指数 (PDI,hPDI,UPDI,PVD) 与全身炎症的联合关联.
- 确定这些饮食模式和炎症水平对所有原因,心血管疾病和癌症死亡率的影响,考虑到肥胖状况.
主要方法:
- 利用国家健康和营养检查调查 (NHANES) 的数据进行横截面和纵向分析.
- 使用24小时回忆来计算HEI-2015,PDI,hPDI,UPDI和PVD得分来评估饮食摄入量.
- 系统性炎症根据C反应性蛋白 (CRP) 水平进行分类,并使用Cox比例危险模型来分析死亡风险.
主要成果:
- 较高的HEI-2015,PDI,hPDI和PVD得分与较低的系统性炎症有关,而UPDI与较高的炎症有关.
- 严重的炎症独立地增加了全因死亡风险.
- 虽然没有发现PDI,hPDI,UPDI或PVD与死亡率之间的直接关联,但HEI-2015得分增加显示,低至中度炎症患者,特别是肥胖患者的死亡风险降低.
结论:
- 按照HEI-2015的测量,坚持健康饮食和消费健康的植物性饮食与减少全身炎症有关.
- 遵守饮食指南可能会减轻与炎症相关的死亡风险,为肥胖和低至中度炎症患者提供潜在的好处.
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